Commitment to a Better You!
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What is JUVÉDERM®?
JUVÉDERM® is a smooth, replenishing injectable gel filler that we use to instantly
to refresh your appearance by smoothing away unwanted lines and bringing back
the natural contours of your face. With just one treatment, you’ll get smooth and
natural-looking results that last up to a year.†
With JUVÉDERM® you get the smooth results you expect, with the improved
comfort you want.Ω.
The exclusive formulation of JUVÉDERM® uses hyaluronic acid (HA), a naturally-
occurring sugar found in your body. It combines with the water in your skin to
instantly smooth lines and wrinkles, enhance lips, and restore lost volume to the
cheeks and jaw-line. In fact, hyaluronic acid facial fillers can even naturally
stimulate collagen production in your skin.1
Everyone will notice, but no one will know.
Where Does It Work?
Everyone’s skin ages differently and JUVÉDERM® may be used to rejuvenate
multiple problem areas.* From smile lines to vertical lip lines, you can smooth away
unwanted wrinkles and restore natural contours.
The History of Hyaluronic Acid
In the 1930s, researchers discovered a natural substance in the body that they
named hyaluronic acid. They found that it played a key role in numerous areas of
the body including the maintenance of skin volume and hydration. In the early
2000's, the first hyaluronic acid facial filler received approval in Canada and the
United States for the correction of facial wrinkles and folds. Today, hyaluronic acid-
based facial fillers are the fastest growing non-surgical aesthetic procedure in
North America.
JUVÉDERM® is made of hyaluronic acid, which occurs naturally in the body and
retains water under the skin to smooth away lines, restore lost volume and
maintain skin hydration. Much like a sponge, its primary function is to bind and
absorb water, which creates volume in the face. In fact, hyaluronic acid can absorb
more than 1,000 times its weight – acting like a super sponge under your skin.
Hyaluronic acid can be thought of as the body's internal moisturizer. As the skin
ages and is exposed to environmental pollutants and ultraviolet rays, the cells
lose the ability to produce hyaluronic acid. As a result, the skin begins to lose
volume, often resulting in the formation of facial wrinkles and folds.
JUVÉDERM® achieves facial rejuvenation by replacing hyaluronic acid lost over
time, smoothing lines, restoring lost skin volume, and keeping your skin hydrated.
Best of all, the results are instantaneous, look natural, and may last up to a year
with no downtime.2


Important JUVÉDERM® Safety Information
JUVÉDERM® injectable gel (including JUVÉDERM® Ultra, JUVÉDERM® Ultra Plus, JUVÉDERM® Ultra XC, and JUVÉDERM® Ultra Plus XC) is indicated for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds).
Treatment side effects are usually mild to moderate, lasting 7 days or less, and include temporary injection-site reactions such as redness, pain, firmness, swelling, and bumps. JUVÉDERM® is not for people with severe allergies.
For more information, please click on the About Safety link at www.juvederm.com or call the Allergan Product Support line at 1-877-345-5372.
JUVÉDERM® injectable gel is available by prescription only.
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* In the United States, JUVÉDERM® is indicated for correction of moderate to severe facial
wrinkles and folds (such as nasolabial folds).
† This includes all JUVÉDERM® injectable gel formulations. Most subjects acquired optimal
correction at initial treatment.
Ω Compared to the non-lidocaine JUVÉDERM® formulation.
1 Frank Wang, Luis A. Garza, Sewon Kang, James Varani, Jeffrey S. Orringer, Gary J. Fisher,
and John J. Voorhees. In Vivo Stimulation of De Novo Collagen Production Caused by Cross-
linked Hyaluronic Acid Dermal Filler Injections in Photodamaged Human Skin. Arch
Dermatol, Feb 2007; 143: 155 – 163
2 Applies to JUVÉDERM® Ultra and JUVÉDERM® Ultra Plus.
- Pinsky, M., Thomas, J., Murphy, D. and Walker, P. JUVÉDERM® Injectable Gel: A
Multicenter, Double-Blind, Randomized Study of Safety and Effectiveness. Aesthetic Surg.
2008;28:17–23.
- Allemann, I. and Baumann, L. Hyaluronic acid gel (JUVÉDERM®) preparations in the
treatment of facial wrinkles and folds. Clinical Interventions in Aging 2008:3(4) 629–634
JUVÉDERM® is part of the Allergan portfolio of products and this is the JUVÉDERM® website.
For information on BOTOX ® Cosmetic, visit www.botoxcosmetic.com.

